Silve Vicent graduated from the University of Navarra in Pamplona (Spain), where he later obtained his doctoral degree on the characterization of the MAPK family and its negative feed-back regulators in lung cancer. He then took a postdoctoral position at the Center for Applied Medical Research (CIMA), where he studied the cellular and molecular mechanisms implicated in lung cancer metastasis to bone. After two years, he moved to Alejandro Sweet-Cordero’s lab at Stanford University. There he developed innovative RNAi-based, functional-genomics approaches and generated new genetically-engineered mouse models of lung cancer to identify synthetic lethal interactions in KRAS tumors and to investigate the role of tumor microenvironment in lung cancer.
In July 2012, Dr. Vicent joined the Program in Solid Tumors and Biomarkers at CIMA-University of Navarra as a Ramon y Cajal investigator and as a fellow of the Marie Curie Program through a Career Integration Grant. Since 2014 he leads the Oncogenes and Effector Targets (OnTarget) group in CIMA and is also an Associated Lecturer at the University of Navarra. His laboratory is interested in identifying new molecular targets and discovering innovative therapeutic strategies for the treatment of mutant KRAS tumors.
He is member of the Navarra Institute of Health (IdisNa), the Spanish Cancer Network CIBERONC, the European Pancreatic Cancer Organoid Group (Precode) and the European Network for the Study of Cholangiocarcinoma (ENSCCA).
Product Enquiry[contact-form-7 404 "Not Found"]