Julian Downward leads the Oncogene Biology Group at the Francis Crick Institute in London. He completed his PhD with Michael Waterfield at the Imperial Cancer Research Fund laboratories in London, where he uncovered the relationship of EGFR to the retroviral erbB oncogene. Julian began working on RAS oncoproteins with Robert Weinberg at the Massachusetts Institute of Technology, prior to starting his own lab at the Cancer Research UK London Research Institute, now part of the Francis Crick Institute. His lab has provided critical insights into molecular mechanisms of signaling networks controlled by RAS proteins and their importance in human tumours.
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